Russell Wilson shook off a first-play interception to account for three touchdowns as the Seahawks handed the San Francisco 49ers their 10th loss of the season Sunday in Santa Clara, Calif.

Wilson ran for one score in the first quarter and found his tight ends for scores on the first two drives of the second half as Seattle won 24-13.

The 49ers fell to 1-10 as they lost to the Seahawks for the eighth straight time. The Seahawks (7-4) remained a game behind the Los Angeles Rams in the NFC West. The Rams (8-3) ended New Orleans’ winning streak at eight games.

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